{"id":2579,"date":"2021-11-17T20:58:55","date_gmt":"2021-11-17T20:58:55","guid":{"rendered":"https:\/\/blog.lib.uiowa.edu\/science\/?p=2579"},"modified":"2021-11-17T21:15:18","modified_gmt":"2021-11-17T21:15:18","slug":"beating-as-one-the-hearts-and-minds-of-fruit-flies","status":"publish","type":"post","link":"https:\/\/blog.lib.uiowa.edu\/science\/2021\/11\/17\/beating-as-one-the-hearts-and-minds-of-fruit-flies\/","title":{"rendered":"Beating as One: The Hearts\u00a0and Minds\u00a0of Fruit Flies\u00a0\u00a0"},"content":{"rendered":"<figure id=\"attachment_2581\" aria-describedby=\"caption-attachment-2581\" style=\"width: 300px\" class=\"wp-caption alignright\"><a href=\"https:\/\/images.nigms.nih.gov\/pages\/DetailPage.aspx?imageid2=6344\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2581 size-medium\" src=\"https:\/\/blog.lib.uiowa.edu\/science\/files\/2021\/11\/drosophila-image_M-300x230.jpg\" alt=\"Two adult fruit flies (Drosophila)\" width=\"300\" height=\"230\" srcset=\"https:\/\/blog.lib.uiowa.edu\/science\/files\/2021\/11\/drosophila-image_M-300x230.jpg 300w, https:\/\/blog.lib.uiowa.edu\/science\/files\/2021\/11\/drosophila-image_M-768x589.jpg 768w, https:\/\/blog.lib.uiowa.edu\/science\/files\/2021\/11\/drosophila-image_M-640x491.jpg 640w, https:\/\/blog.lib.uiowa.edu\/science\/files\/2021\/11\/drosophila-image_M.jpg 1024w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><figcaption id=\"caption-attachment-2581\" class=\"wp-caption-text\">Two adult fruit flies (Drosophila). Source:<br \/>Dr. Vicki Losick, MDI Biological Laboratory, www.mdibl.org<br \/>Credit Line:<br \/>Courtesy of MDI Biological Laboratory<\/figcaption><\/figure>\n<p><span data-contrast=\"auto\">University of Iowa Biology Professors Alan Kay and Daniel Eberl&nbsp;have discovered&nbsp;<\/span><a href=\"https:\/\/now.uiowa.edu\/2021\/10\/heart-beats-almost-our-own\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">a tiny heart&nbsp;that beats&nbsp;inside the&nbsp;brain&nbsp;of fruit flies<\/span><\/a><span data-contrast=\"auto\">. The heart, which is a secondary heart to the main heart, pumps on its own and provides the circulation for the antennae of the fruit fly. The pumping action of this secondary heart in the brain is also thought to cleanse the brain of waste through agitation when the heart beats in lieu of a circulation system in the brain as found in humans. Their discovery of the \u201chead-heart&#8221; in fruit flies was recently published in the <\/span><a href=\"https:\/\/search.lib.uiowa.edu\/permalink\/f\/18gddib\/TN_cdi_proquest_miscellaneous_2577730700\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Journal of Experimental Biology<\/span><\/a><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">&nbsp;<\/span><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4876951\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Fruit flies are&nbsp;a model organism<\/span><\/a><span data-contrast=\"auto\">&nbsp;for research for several reasons. They have a short reproductive cycle&nbsp;which means that researchers can observe the&nbsp;consequences of&nbsp;changes in genetics quickly over several generations.&nbsp;In 1933&nbsp;T.H. Morgan&nbsp;received a&nbsp;Nobel Prize after his research with fruit flies&nbsp;led&nbsp;him to&nbsp;understand&nbsp;the&nbsp;role of&nbsp;chromosomes&nbsp;in&nbsp;genetics.&nbsp;Fruit flies are instrumental in other types of research besides genetics. They&nbsp;have been&nbsp;studied&nbsp;to learn more about behavior, neuroscience, and aging, for example.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">&nbsp;<\/span><\/p>\n<p><span data-contrast=\"auto\">In addition to Morgan&#8217;s Nobel Prize in 1933, research&nbsp;completed&nbsp;with fruit flies has resulted in an additional five&nbsp;<\/span><a href=\"https:\/\/www.theguardian.com\/science\/2017\/oct\/07\/fruit-fly-fascination-nobel-prizes-genetics\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Nobel Prizes<\/span><\/a><span data-contrast=\"auto\">&nbsp;being awarded in later years.&nbsp;Most recently, Jeffrey C. Hall, Michael&nbsp;Robash, and Michael W. Young won the Nobel Prize in 2017 for discovering the molecular underpinnings of circadian rhythms in fruit&nbsp;flies.&nbsp;NASA studies&nbsp;<\/span><a href=\"https:\/\/www.nasa.gov\/ames\/fruit-fly-lab\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">fruit flies&nbsp;in space<\/span><\/a><span data-contrast=\"auto\">&nbsp;to help with our understanding of microgravity and how it&nbsp;affects human&nbsp;physiology.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">&nbsp;<\/span><\/p>\n<p><span data-contrast=\"auto\">Read more about fruit fly research at the UI Libraries using the list below, and search <a href=\"https:\/\/search.lib.uiowa.edu\/primo-explore\/search?vid=01IOWA\" target=\"_blank\" rel=\"noopener\">InfoHawk+<\/a> to find more.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\"> If you need help, <a href=\"https:\/\/www.lib.uiowa.edu\/sciences\/contact\/\" target=\"_blank\" rel=\"noopener\">contact a Sciences Librarian<\/a> for a research consultation.<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/search.lib.uiowa.edu\/permalink\/f\/18gddib\/TN_cdi_askewsholts_vlebooks_9783319183268\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Life Extension: Lessons from Drosophila<\/span><\/a><span data-contrast=\"none\">&nbsp;this&nbsp;book provides readers with an overview of current research on the use of the Drosophila model to understand the genetic, molecular and physiological mechanisms that underlie the aging process.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">&nbsp;<\/span><\/li>\n<li><a href=\"https:\/\/search.lib.uiowa.edu\/permalink\/f\/18gddib\/TN_cdi_askewsholts_vlebooks_9780123870193\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Recent Advances in the Use of Drosophila in Neurobiology and Neurodegeneration<\/span><\/a><span data-contrast=\"none\">&nbsp;This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia.&nbsp;<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">&nbsp;<\/span><\/li>\n<li><a href=\"https:\/\/search.lib.uiowa.edu\/permalink\/f\/18gddib\/TN_cdi_proquest_ebookcentral_EBC270986\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">An Atlas of Drosophila Genes: Sequences and Molecular Features<\/span><\/a><span data-contrast=\"none\">&nbsp;&nbsp;The&nbsp;aim of this reference is to summarize information about most of the drosophila genes for which the complete nucleotide sequence is known.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">&nbsp;<\/span><\/li>\n<li><a href=\"https:\/\/search.lib.uiowa.edu\/permalink\/f\/9i2ftm\/01IOWA_ALMA21647524930002771\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Drosophila models for human diseases<\/span><\/a><span data-contrast=\"none\">&nbsp;&nbsp;This&nbsp;book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">&nbsp;<\/span><\/li>\n<li><a href=\"https:\/\/search.lib.uiowa.edu\/permalink\/f\/18gddib\/TN_cdi_askewsholts_vlebooks_9780195360325\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Progress and prospects in evolutionary biology: the Drosophila&nbsp;model<\/span><\/a><span data-contrast=\"none\">&nbsp;&nbsp;The&nbsp;explosion in use of Drosophila in evolutionary studies has resulted in an explosion of knowledge which has not heretofore been gathered into a single volume. The book spans the full range of evolutionary studies: population genetics, ecology, ecological genetics, speciation, phylogenetics, genome evolution, molecular evolution, and development.&nbsp;<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">&nbsp;<\/span><\/li>\n<li><a href=\"https:\/\/search.lib.uiowa.edu\/permalink\/f\/18gddib\/TN_cdi_askewsholts_vlebooks_9783030236298\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">The Drosophila Model in Cancer<\/span><\/a><span data-contrast=\"none\">&nbsp;This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">&nbsp;<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>University of Iowa Biology Professors Alan Kay and Daniel Eberl&nbsp;have discovered&nbsp;a tiny heart&nbsp;that beats&nbsp;inside the&nbsp;brain&nbsp;of fruit flies. The heart, which is a secondary heart to the main heart, pumps on its own and provides the circulation for the antennae of the fruit fly. The pumping action of this secondary heart in the brain is also<a class=\"more-link\" href=\"https:\/\/blog.lib.uiowa.edu\/science\/2021\/11\/17\/beating-as-one-the-hearts-and-minds-of-fruit-flies\/\">Continue reading <span class=\"screen-reader-text\">&#8220;Beating as One: The Hearts\u00a0and Minds\u00a0of Fruit Flies\u00a0\u00a0&#8220;<\/span><\/a><\/p>\n","protected":false},"author":223,"featured_media":2581,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[269,268,271,270],"syndication":[41,37],"_links":{"self":[{"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/posts\/2579"}],"collection":[{"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/users\/223"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/comments?post=2579"}],"version-history":[{"count":3,"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/posts\/2579\/revisions"}],"predecessor-version":[{"id":2583,"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/posts\/2579\/revisions\/2583"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/media\/2581"}],"wp:attachment":[{"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/media?parent=2579"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/categories?post=2579"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/tags?post=2579"},{"taxonomy":"syndication","embeddable":true,"href":"https:\/\/blog.lib.uiowa.edu\/science\/wp-json\/wp\/v2\/syndication?post=2579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}